Bone tissue is a complex structure, consisting of mineralized collagen fibers and a variety of non-collagenous proteins, including proteoglycans such as biglycan and decorin. These proteoglycans ...

What keeps bones able to remodel themselves and stay healthy? A team has discovered clues to the key function of non-collagen protein compounds and how they help bone cells react to external load. The ...

A recent study has uncovered the essential roles of two proteoglycans, biglycan and decorin, in maintaining bone mass, water retention, and bulk/in situ mechanical competence. Through the use of ...

Around 500 million years ago, early vertebrates in the seas became fish, adopting an inner skeleton and a flexible spine based on a nanocmposite of fibers and mineral, known as bone material. This ...

Strong bones need more than calcium, vitamin and minerals work together for ...