The intracellular environment is highly compartmentalized; biomolecules (nucleic acids, proteins, lipids and so on) are spatiotemporally organized to form functional modules, signal pathways and ...

What are spherical nucleic acids (SNAs)? What do they consist of and how do they differ from linear nucleic acids? Spherical nucleic acids are structures that are made by taking a nanoparticle ...

内分泌信号，特别是雌激素信号，对维持两性哺乳动物的健康骨骼至关重要。成人雌激素信号缺乏的一个主要后果是破坏骨形成和吸收之间的平衡，吸收速度超过形成速度，导致净骨丢失，最终导致骨质疏松。 D1型肢带型肌营养不良症(LGMDD1)是由DNAJB6基因的主要 ...

DNA is the poster child for high-specificity binding. As long as their base sequences match, two complementary strands of DNA can navigate through a sea of biomolecules, find each other, and hold fast ...

The research focus of the Müller group is the bioinorganic chemistry of nucleic acids with a particular emphasis on the generation, characterization as well as application of nucleic acids including ...

Quantification of nucleic acid concentrations is often performed by measuring light absorption in UV-VIS spectrometers. There are a few challenges faced in this measurement method. In UV-VIS ...