Studies on the association of methylenetetrahydrofolate reductase (MTHFR) genotype in childhood acute lymphoblastic leukemia (ALL) have yielded conflicting results. The present study examines this ...

Serotonin (5-HT) receptors 2A are expressed in brain regions involved in memory and learning processes. Recently, a functional single nucleotide polymorphism in the 5-HT2A receptor gene leading to an ...

In this issue, Gryshchenko et al 1 report that a known single nucleotide polymorphism (SNP) in the promoter region of MDM2 is associated with treatment-free and overall survival in chronic lymphocytic ...

Phase 1 study of picoplatin (pico) in combination with 5-fluorouracil (FU) and leucovorin (LV) as initial therapy in subjects with metastatic colorectal cancer (CRC) No significant financial ...

Toll-like receptors (TLRs) are essential components of the immune response to fungal pathogens. We examined the role of TLR polymorphisms in conferring a risk of invasive aspergillosis among ...

1982 The Human Polymorphism Study Center, the first academic institution to propose the systematic study of polymorphisms, is founded in Paris. Its primary objective: to make an inventory of all ...