When starting class design in Python, the first weapon many developers pick up is the "instance method." However, as the scale grows, they hit walls like "processing that doesn't need to create an ...

smellcheck is a Python code smell detector and refactoring catalog. It works as a pip-installable CLI, GitHub Action, pre-commit hook, or Agent Skills plugin for AI coding assistants. No dependencies.

This page is a curated collection of IPython notebooks that are notable for some reason. Feel free to add new content here, but please try to only include links to notebooks that include interesting ...

The cytochrome P450 2D6 (CYP2D6) is a key xenobiotic-metabolizing enzyme involved in the clearance of many drugs. Genetic polymorphisms in CYP2D6 contribute to the large inter-individual variability ...

The calculation of derivatives is ubiquitous in science and engineering. In thermodynamics, in particular, state properties can be expressed as derivatives of thermodynamic potentials. The manual ...

Beijing City Key Laboratory of Polymorphic Drugs, Center of Pharmaceutical Polymorphs, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050 ...