Given that most informative chromatin contacts occur within a limited genomic distance (typically within 2 Mb), BandHiC adopts a banded storage scheme that stores only a configurable diagonal ...

This important study introduces a fully differentiable variant of the Gillespie algorithm as an approximate stochastic simulation scheme for complex chemical reaction networks, allowing kinetic ...

Data-driven models that act as surrogates for computationally costly 3D topology optimization techniques are very popular because they help alleviate multiple time-consuming 3D finite element analyses ...

DNA methylation plays a fundamental role in regulating gene expression and maintaining genomic stability. Errors in methylation patterning result in impaired cellular function and abnormal gene ...

A Perceptron is a basic learning algorithm invented in 1959 by Frank Rosenblatt. It is meant to mimic the working logic of a biological neuron. The human brain is basically a collection of many ...

The computational neuroscience field has heavily concentrated on the modeling of neuronal functions, largely ignoring other brain cells, including one type of glial cell, the astrocytes. Despite the ...