Abstract: The Nelder-Mead simplex method is a well-known algorithm enabling the minimization of functions that are not available in closed-form and that need not be differentiable or convex.

Abstract: Optimization problems lie at the core of scientific and engineering endeavors. Solutions to these problems are often compute-intensive. To fulfill their compute-resource requirements, ...

Purpose To compare the recurrence rates of herpes simplex virus type 1 (HSV-1) keratitis (HSK) and varicella zoster virus (VZV) keratitis (VZK). Methods This was a cohort study of patients attending ...

We report a baby with neonatal herpes simplex virus (HSV) encephalitis concurrent with Rrhesus (Rh) incompatibility. He was delivered by a Ggravida 2 mother with a history of miscarriage in her ...

Design Prospective parallel randomised controlled open-label superiority trial. Setting 76 community pharmacies across New Zealand between 10 September 2015 and 13 December 2017. Participants 952 ...

Genital herpes is a lifelong infection. While available treatments can manage symptoms, they cannot cure the infection or ...

Objectives Treatment of rheumatoid arthritis (RA) relies on immunomodulatory drugs that can compromise immunity, inducing secondary immunodeficiency (SID). However, features of SID, such as ...

This study sought to determine the utility of an interlocking finger task in screening for parietal lobe dysfunction. The ability of 69 patients to imitate a standardised set of four interlocking ...

The Global Financial Stability Report provides semiannual assessments of global financial markets and addresses emerging market financing in a global context.* ...

A woman in her early 20s underwent bilateral photorefractive keratectomy (PRK) for correction of myopia. She developed ...