A new multiplex immunofluorescence workflow using standard laboratory equipment and open-source software enables detailed ...

Plant immunity research has undergone a transformative shift with the advent of spatial and single-cell technologies, ...

If you use cell2location please cite our paper: Kleshchevnikov, V., Shmatko, A., Dann, E. et al. Cell2location maps fine-grained cell types in spatial transcriptomics ...

Contributed by Howard Y. Chang; received November 19, 2024; accepted February 20, 2025; reviewed by Jellert Gaublomme and David A. Quigley The spatial organization of cells within tissues plays a ...

The field of neuroimmunity is at the forefront of understanding the complex etiology of neurological disorders, which remain challenging to diagnose and treat due to their intricate pathologic ...

Over the past two decades, high‑throughput sequencing has dramatically expanded our understanding of the gut microbiome's composition.

Aging affects every organ in the body, yet we still know little about how the ovary changes over time. In a new study published in Nature Aging, Yale researchers created one of the most detailed maps ...

We developed a statistical method for Integrative and Reference-Informed Spatial Domain Detection for Spatial Transcriptomics. IRIS is a reference-informed integrative method for detecting spatial ...

无颌脊椎动物七鳃鳗的大脑相对简单，了解其工作原理可能为脊椎动物大脑进化提供宝贵见解。研究者结合单核RNA测序和空间转录组学技术，构建了成年七鳃鳗大脑的三维图谱。

Study: Common polyethylene microplastics may worsen fatty liver disease. In mice on high-fat diets, exposure doubled liver ...

, Harvard Medical School, Boston, Massachusetts. 13Broad Institute of Harvard and MIT, Cambridge, Massachusetts. 20Department of Pathology, Dana Farber Cancer Institute, Boston, Massachusetts.