Introduction: Hybrid modeling combining First-Principles with machine learning is becoming a pivotal methodology for Biopharma 4.0 enactment. Chinese Hamster Ovary (CHO) cells, being the workhorse for ...

Yoshua Bengio, Yann LeCun, and Geoffrey Hinton are recipients of the 2018 ACM A.M. Turing Award for breakthroughs that have made deep neural networks a critical component of computing. Research on ...

Gradient descent based algorithms for training DNNs have been successful in achieving human-like accuracy in several cognitive tasks. The training typically involves three stages. During forward ...

2Department of Disease Data Science, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan. 3Department of Frontier Science for Cancer and Chemotherapy, Graduate School of Medicine, Osaka ...