CD8 T cell exhaustion is a key underlying factor limiting immunity in chronic infections and cancer. Persistent antigen exposure antagonizes formation of functional memory CD8 T cells that provide ...

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease lacking effective disease-modifying therapies. To better understand the mechanisms underlying motor neuron degeneration, we ...

After several examples of undisclosed alterations in reagent suppliers’ antibody catalogues surfaced, researchers call for transparency to rebuild trust.