The use of microarrays to analyse gene expression on a global level has recently received a great deal of attention. There has been much speculation about the power of this approach in the analysis of ...

Genes that follow similar expression trajectories in response to stress or stimulus tend to share biological functions. Thus, it is reasonable and common to cluster genes by expression trajectories.

† ∥ † Key Laboratory of Systems Biomedicine (Ministry of Education) and ∥ School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, People’s Republic of China ‡ Shanghai Municipal ...

Abstract: In unsupervised learning literature, the study of clustering using microarray gene expression datasets has been extensively conducted with nonnegative matrix factorization (NMF), spectral ...

Background Wolf–Hirschhorn syndrome (WHS) is a contiguous gene deletion syndrome involving variable size deletions of the 4p16.3 region. Seizures are frequently, but not always, associated with WHS.

Abstract: In the diagnosis and treatment of cancer, cancer classification is a vital issue. Gene selection is much needed to solve the high dimensionality issue in microarray data, small sample size, ...

Exploration means looking around, observing, describing and mapping undiscovered territory, not testing theories or models. The goal is to discover things we neither knew or expected, and to see ...