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过氧化氢自供纳米酶系统,通过铁死亡/炎性死亡及钙离子超载诱导的 ...
摘要铁死亡是一种依赖铁元素且非凋亡途径的细胞死亡方式,在治疗具有凋亡抗性的癌症方面越来越受到关注。然而,过氧化氢(H2O2)供应不足会阻碍高毒性自由基的持续生成,从而削弱铁死亡效应。此外,单独使用铁死亡诱导剂在癌症治疗中的效果往往有限。因此,通过增加H2O2供应来促进铁死亡,以及 ...
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