Your car's key fob suddenly stops unlocking the doors or starting the vehicle. The dealership checks it and says the fob has lost communication with the car and needs to be reprogrammed. Then comes ...

During direct cardiac reprogramming, cardiogenic transcription factors (TFs) cooperatively reshape the epigenomic landscape by activating cardiac enhancers, which describe a common epigenetic ...

Significant opportunities in the cancer metabolism-based therapeutics market include leveraging precision medicine to target unique cancer cell metabolic pathways, driving personalized treatment ...

Signal transduction and gene regulation are at the heart of cell and developmental biology, driving cell fate decisions and tissue homeostasis. In cancer, ...

Under NIR irradiation, MPDA/B@M’s photothermal effect directly eradicates pathogens while upregulating HSP70 to enhance host inflammation tolerance. This synergizes with bufalin’s anti-inflammatory ...

Background Intrahepatic cholangiocarcinoma (iCCA) is a highly invasive malignancy characterized by marked intratumoral and microenvironmental heterogeneity. However, how metabolic reprogramming in ...

Contributed by Myles Brown, November 6, 2019 (sent for review July 9, 2019; reviewed by Douglas Yee and Wilbert Zwart) In this study, we integrated FOXA1 cistrome, epigenetic histone marks, and ...

Scientists say they have built a cell from scratch for the first time that can feed, grow and replicate like a natural cell.

A gastrointestinal oncologist told Newsweek that the early-stage findings are a “major step forward” in targeting colon ...