Background Congenital aortic stenosis (ConAoS) accounts for approximately 4%–8% of all congenital heart diseases. Chronic ...

Yet, arterial stiffness has emerged as a prominent marker of cardiovascular risk, first in high-risk patients (eg, end-stage renal disease [ESRD]), then in hypertension, and now in nearly all ...

Abstract: A high-precision numerical method is presented to model acoustic wave propagation along a duct with discontinuities. The discontinuous duct can be divided into homogeneous and inhomogeneous ...

Osteoarthritis (OA), the most prevalent joint disorder associated with aging, is characterized by impaired extracellular matrix (ECM) synthesis and the degradation of articular cartilage. It is ...

1 Department of Mechanical and Aerospace, Brunel University, London, UK. 2 Department of Design, Brunel University, London, UK. This paper is to review the theory of thin-walled beam structures of the ...

Vascular pericytes, important mural cells that retain progenitor cell properties and protect vascular integrity in healthy tissues, are often associated with tumor development, but their functions in ...

Abstract: Contact-rich tasks, wherein multiple contact transitions occur in a series of operations, have been extensively studied for task automation. Precision assembly, a typical example of ...

Dipartimento di Scienza Applicata e Tecnologia, Politecnico di Torino, C.so Duca degli Abruzzi 24, Turin 10129, Italy PolitoBIOMed Lab, Politecnico di Torino, C.so Duca degli Abruzzi 24, Turin 10129, ...

Titin, the largest protein known, forms an elastic myofilament in the striated muscle sarcomere. To establish titin’s contribution to skeletal muscle passive stiffness, relative to that of the ...

How organ-shaping mechanical imbalances are generated is a central question of morphogenesis, with existing paradigms focusing on asymmetric force generation within cells. We show here that organs can ...

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The standard formula for geometric stiffness matrix calculation, which is convenient for most engineering applications, is seen to be unsatisfactory for large strains because of poor accuracy, low ...