Genes that follow similar expression trajectories in response to stress or stimulus tend to share biological functions. Thus, it is reasonable and common to cluster genes by expression trajectories.

Background Wolf–Hirschhorn syndrome (WHS) is a contiguous gene deletion syndrome involving variable size deletions of the 4p16.3 region. Seizures are frequently, but not always, associated with WHS.

Exploration means looking around, observing, describing and mapping undiscovered territory, not testing theories or models. The goal is to discover things we neither knew or expected, and to see ...