PARP inhibitors kill cancer cells by trapping poly(ADP-ribose) polymerase 1 (PARP1) on DNA. A study now shows that cancer cells use a specialized form of autophagy to extract and degrade trapped PARP1 ...

PitchBook’s principal fund strategies analyst provides a lesson in the parlance of private markets as they open to a broader spectrum of investors.

The finding that spermine molecules in cells bind to iron to prevent it unleashing ferroptosis, a type of cell death, opens up strategies for treating tissue damage and cancer.

About nine-in-ten adults under 40 say buying a home is harder than it was for their parents, as rising prices and mortgage rates push homeownership further out of reach. Lawmakers in at least 16 ...

PM-in-waiting Andy Burnham plans to give more power to UK cities and regions, which raise only 8% of tax ⁠revenues versus a 37% rich-country average. But decentralisation elsewhere has proven better ...

Majorities in most of the three dozen countries we’ve surveyed this year express an unfavorable view of Israel and little or no confidence in Prime Minister Benjamin Netanyahu. These findings come ...