Abstract: We propose QGENE, a quantum-enhanced framework for approximate string matching used to perform local DNA sequence alignment. QGENE is a dynamic programming model with recursive functions ...
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Multiple sequence alignment (MSA) lies at the heart of comparative genomics, structural biology and evolutionary inference. By arranging three or more nucleotide or amino acid sequences in a matrix, ...
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The authors acknowledge support from the National Science Foundation of China (Grant Nos. 22025302 and 22533003) and the National Key R&D Program of China (Grant No. 2022YFA1203203). We thank Xuanyu ...
Open-access databases such as the European Nucleotide Archive (ENA) contain more than 2.4 million bacterial genomes, and this number continues to grow rapidly. Until now, searching these vast ...
Katie has a PhD in maths, specializing in the intersection of dynamical systems and number theory. She reports on topics from maths and history to society and animals. Katie has a PhD in maths, ...
Sequence alignments are often used to analyze genomic data. However, such alignments are often only calculated and compared on small sequence intervals for analysis purposes. When comparing longer ...
provides a genome-wide query coverage metric (qcovGnm), which enables accurate interpretation of search results - particularly for circular queries (such as plasmid, virus, and mtDNA) against both ...
This is a secondary release of the PhyIN method for trimming alignments for phylogenomics work. It includes the standalone phython code. The primary release of PhyIN ...