We developed a statistical method for Integrative and Reference-Informed Spatial Domain Detection for Spatial Transcriptomics. IRIS is a reference-informed integrative method for detecting spatial ...

Contributed by Howard Y. Chang; received November 19, 2024; accepted February 20, 2025; reviewed by Jellert Gaublomme and David A. Quigley The spatial organization of cells within tissues plays a ...

Cellist is a computational method to perform cell segmentation on high-resolution spatial transcriptomics (ST) data, including sequncing-based (e.g. Stereo-seq and ...

A new multiplex immunofluorescence workflow using standard laboratory equipment and open-source software enables detailed ...

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Plant immunity research has undergone a transformative shift with the advent of spatial and single-cell technologies, ...

Abstract: Spatial transcriptomics has revolutionized the ability to investigate transcriptional patterns within tissue morphology. However, many ST clustering pipelines operate on a single preselected ...

Summary: Researchers constructed a high-resolution spatial map of the molecular changes induced by selective serotonin reuptake inhibitors (SSRIs) within the brain’s primary serotonin hub.

Whole-transcriptome profiling across a large tissue capture area can generate 2x more unique genes per sample than probe-based technologies SAN DIEGO, June 8, 2026 /PRNewswire/ -- Illumina, Inc.

1 Translational Gastroenterology And Liver Unit, University of Oxford, Oxford, United Kingdom 2 Centre for Computational Biology, Weatherall Institute of Molecular Medicine, University of Oxford, ...

Researchers at The University of Texas MD Anderson Cancer Center have developed a spatial map of muscle-invasive bladder cancer, revealing how tumor cell states, immune environments and therapeutic ...